ea0028p201 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2012
O'Reilly Michael
, Hazlehurst John
, Lebbe Marie
, Stewart Paul
, Tomlinson Jeremy
, Arlt Wiebke
Polycystic ovary syndrome (PCOS) is a triad of insulin resistance, hyperandrogenism and anovulation. PCOS is associated with increased adrenocortical drive and 5alpha-reductase activity, which may have adverse metabolic consequences. Here we analysed the relationship of urinary androgen and glucocorticoid metabolite excretion with markers of insulin resistance in a large PCOS cohort. We compared results from 127 PCOS patients fulfilling Rotterdam diagnostic criteria with 100 B...